Clinical Trial
Study Details
Study Overview
This study is testing a potential new medicine, NNC6019-0001, for people who have a heart disease due to TTR amyloidosis.The study will look at if this medicine can reduce the symptoms of a heart disease due to TTR amyloidosis, such as heart failure. Participants will either get NNC6019-0001 (apotential new medicine) or placebo (a medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting NNC6019-0001 is two times higher than getting placebo. NNC6019-0001 is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe yet. Participants will get an infusion of the study medicine 13 times, once every 4 weeks. The study will last for about 64 weeks after the first dose of medicine. Participants cannot participate in this study if they have a heart disease other than a heart disease due to TTR amyloidosis.
Contacts and Locations
Mayo Clinic Arizona
Phoenix, Arizona 85054
United States
Cedars-Sinai Medical Center_Los Angeles
Beverly Hills, California 90211
United States
Stanford Hlth Cre-Boswell Clin
Stanford, California 94305
United States
Mayo Clinic Jacksonville
Jacksonville, Florida 32224
United States
NW Univ-Bluhm Cardiovasc Inst
Evanston, Illinois 60208
United States
Univ of MD Schl of Med
Baltimore, Maryland 21201
United States
University of Maryland School of Medicine
Baltimore, Maryland 21201
United States
Mayo Clinic Rochester
Rochester, Minnesota 55905
United States
Oregon Hlth Sci Univ-Portland
Portland, Oregon 97239-4501
United States
University of Calgary_Cardiology
Calgary Alberta T2N 4Z6
Canada
Ctr for Cardiovascular Innovation
Vancouver British Columbia V5Z 1M9
Canada
II. interni klinika VFN - Kardiologie a angiologie
12808 Prague
Czechia
Ap-Hp-Hopital Henri Mondor
94000 Créteil
France
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil
31059 Toulouse
France
Centre Hospitalier Universitaire de Toulouse-Hopital Rangueil-1
31059 Toulouse Cedex 9 TSA 50032
France
UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie
69120 Heidelberg
Germany
LMU Klinikum München Klinik und Poliklinik 1
81377 München
Germany
Universitätsklinikum Münster - Klinik für Kardiologie I
48149 Münster
Germany
Universitatsklinikum Wurzburg AöR
97078 Würzburg
Germany
Universitatsklinikum Würzburg - Zentrum für Herzinsuffizienz
97078 Würzburg
Germany
Fondazione Toscana Gabriele Monasterio - Dipartimento Cardiotoracico - UOC Cardiologia e Medicina Cardiovascolare
56124 Pisa Pi
Italy
Centro per lo Studio e la Cura delle Amiloidosi Sistemiche Fondazione IRCCS Policlinico San Matteo
27100 Pavia PV
Italy
Hospital of the University of Occupational and Environmental Health, Cardiology, Nephrology
Fukuoka
807-8556
Japan
Hospital of the University of Occupational and Environmental Health
Fukuoka
807-8556
Japan
Hiroshima University hospital, Cardiovascular Medicine
Hiroshima
734-8551
Japan
Hiroshima University hospital_Cardiovascular Medicine
Hiroshima
734-8551
Japan
Kumamoto University Hospital, Cardiovascular Medicine
Kumamoto-shi, Kumamoto
860-8556
Japan
Shinshu University Hospital, Department of Neurology
Nagano
390-8621
Japan
Nagasaki University Hospital, Cardiovascular Medicine
Nagasaki
852-8501
Japan
Okayama University Hospital_Cardiovascular Medicine
Okayama-shi, Okayama
700-8558
Japan
UMC Groningen afdeling Cardiologie
9713 GZ Groningen
Netherlands
UMC Groningen
9713 GZ Groningen
Netherlands
Universitair Medisch Centrum Utrecht
3584 CX Utrecht
Netherlands
Hospital da Senhora da Oliveira - Guimarães
4835-044 Guimarães
Portugal
ULS Do Alto Ave, E.P.E. - Hospital Senhora da Oliveira - Guimarães
4835-044 Guimarães
Portugal
Unidade Local de Saude do Alto Ave, E.P.E.
4835-044 Guimarães
Portugal
ULS De Tras-Os-Montes E Alto Douro E.P.E. - Unidade Hospitalar de Vila Real
5000-508 Vila Real
Portugal
Hospital Universitario Puerta de Hierro Majadahonda
28222 Majadahonda Madrid
Spain
Hospital Universitario Puerta de Hierro Majadahonda
28222 Madrid
Spain